In the male body, DIM acts as an inhibitor for a particular enzyme called aromatase. This makes it that much more potent of a regulating substance. We didn’t discuss how DIM may help increase testosterone while reducing harmful estrogen in males. We talked about the way DIM promotes “good estrogen” while decreasing “bad estrogen” above.
DIM, Aromatase, Estrogen, and Testosterone Since DIM promotes the opposite, it’s gotten a lot of attention as a breast cancer-preventing compound. In breast cancer studies, a low ratio of 2-OHE1 to 16-OHE1 suggests a high risk of developing invasive breast cancer amongst premenopausal women.
DIM and EstrogenĮstrogen, often referred to as the female hormone, comes in several forms.ĭIM promotes the production of 2-hydroxy estrone, a less potent form of estrogen that scientists sometimes refer to as “good estrogen.” 2-hydroxy estrone (2-OHE1) seems to be anticarcinogenic and protective against tumors, especially those that develop in hormonally driven cancers.Īt the same time, DIM reduces the effects of 16-alpha-hydroxy estrone, which some colloquially call “bad estrogen.” 16-alpha-hydroxy estrone (16-OHE1) forms a strong bond with our bodies’ estrogen receptors and promotes cell growth, including the growth of cancerous cells. It does this by affecting one of the most prominent hormonal players in our body: estrogen. DIM helps manage our hormones and keep them in a balanced state. Unbalanced hormones also affect our brains, bone health, and more. And, for men, prostate health and sexual function can become a concern. Acne may develop even though we’re way past our teenage years. For example, our risk for certain cancers increases, and we may have trouble with our skin. When hormones go haywire, we end up with all sorts of issues. Why Our Bodies Need DIMĭIM is one of the many reasons doctors and dieticians are constantly telling us to eat our veggies! Our bodies need DIM to keep our hormones from getting out of whack. It’s this balancing effect that makes DIM supplements effective at regulating hormones, especially as we age. In other words, DIM helps our bodies get rid of what it doesn’t need and create what it does. These enzymes are involved in the elimination and metabolism of toxins, carcinogens, and steroid hormones like estrogen. That’s a chemical reaction that generates a bunch of biologically active substances, including DIM.ĭIM works to modulate the expression and activity of certain enzymes.
Then, in our stomachs, I3C undergoes acid-catalyzed condensation. When we eat cruciferous vegetables, our bodies break them down to create I3C. Glucobrassicin is a naturally occurring compound found in cruciferous vegetables like broccoli and cabbage. I3C comes from the breakdown of glucobrassicin. DIM Explainedĭiindolylmethane is a natural substance that forms from indole-3-carbinol (I3C). But, there’s plenty of evidence backing DIM’s potent and beneficial effects.īefore we dig into the science, though, it might be helpful to define what DIM is, where it comes from, and how it works. If you’re feeling skeptical about diindolylmethane supplements, we understand. What Are DIM Supplements?ĭiindolylmethane supplements are a convenient way to obtain a necessary natural compound that has powerful hormone regulating effects.īy putting your hormones in balance, diindolylmethane (DIM) supplements could counter the effects of aging as well as reduce your risks for certain cancers. It’s also available in convenient supplement form.Īre you an older male experiencing the ill effects of shifting hormones and want to get your youthful edge back? Then taking a diindolylmethane supplement might be your best bet. That’s where DIM supplements hold a lot of promise.ĭiindolylmethane or DIM is a natural compound that you can get from cruciferous vegetables. Unfortunately, when that happens, they can easily end up out of balance. Share Why It’s Important to Regulate EstrogenĪs we age, our hormones tend to shift.
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